The Clinical Impact of Genomics in the Pediatric Oncology
Center of Life Sciences, Room 11081 3 Blackfan Circle, Boston, MA, United StatesDFCI Genomics Meetup Katherine Janeway, MD Pediatric Oncology Dana-Farber Cancer Institute Pizza is provided.
DFCI Genomics Meetup Katherine Janeway, MD Pediatric Oncology Dana-Farber Cancer Institute Pizza is provided.
Data Science Training Session Hajime Uno Assistant Professor, Department of Data Science Dana-Farber Cancer Institute
Data Science Training Session Kelly Street, Research Fellow Etai Jacob, Research Fellow In this short course, we will introduce some of the most widely used tools for single cell analysis. We will describe common experimental methods utilized in the community to generate single cell RNA-seq data and demonstrate modern pre-processing and analysis pipelines. In addition, […]
Caroline Buckee, Department of Biostatistics Harvard TH Chan School of Public Health How do we predict the pandemic? Michael Mina, Department of Epidemiology Harvard TH Chan School of Public Health The importance and challenges of testing for COVID-19 Natalie Dean, Department of Biostatistics, University of Florida How we evaluate the efficacy of potential therapies and […]
Frontiers in Biostatistics Seminar Noah Simon, Ph.D. Associate Professor Department of Biostatistics University of Washington To build inferential or predictive survival models, it is common to assume proportionality of hazards and fit a model by maximizing the partial likelihood. This has been combined with non-parametric and high dimensional techniques, eg. spline expansions and penalties, to flexibly build […]
Frontiers in Biostatistics Webinar Marianne Menictas Postdoctoral Fellow, Department of Statistics Harvard University Mobile health (mHealth) technologies are increasingly being employed to deliver interventions to users in their natural environments. With the advent of increasingly sophisticated sensing devices (e.g., GPS) and phone-based EMA, it is becoming possible to deliver interventions at moments when they can […]
A conversation with Jeff Leek, PhD, Johns Hopkins University. Moderator: Rafael Irizarry. Registration required. https://dfci.zoom.us/webinar/register/WN_XscX-d21RqylhDCXzvP2-Q A recording of the talk is available on our YouTube channel.
A conversation with Natalie Dean, PhD University of Florida Moderator: Rafael Irizarry A recording of the talk is available on our YouTube channel.
A conversation with Marc Lipsitch, PhD Harvard TH Chan School of Public Health Moderator: Rafael Irizarry Registration required: https://dfci.zoom.us/webinar/register/WN_F_ROPV-RRNyXGoXaoTWFNw A recording of the talk is available on our YouTube channel.
A conversation with Daniela Witten, PhD University of Washington Moderator: Rafael Irizarry Registration required: https://dfci.zoom.us/webinar/register/WN_YvsckwdGSxmTT-GeyLGOOA A recording of the talk is available on our YouTube channel.
A conversation with Elisabeth Bik, PhD, Microbiome & Science Integrity Consultant, Harbers Bik LLC Moderator: Rafael Irizarry, PhD We are pleased to announce a new weekly Zoominar for Data Science. Rather than a traditional seminar format, Rafael Irizarry will moderate a Q&A with invited speakers on various topics in data science. Join us for these […]
A conversation with Gillian Haney, Director of Infectious Disease Surveillance and Informatics, Massachusetts Department of Public Health and Catherine (Katie) Brown, State Public Health Veterinarian, Massachusetts Department of Public Health Moderator: Rafael Irizarry We are pleased to announce a new weekly Zoominar for Data Science. Rather than a traditional seminar format, Rafael Irizarry will moderate […]
A conversation with John P.A. Ioannidis, C. F. Rehnborg Professor In Disease Prevention In The School Of Medicine, Professor Of Medicine, Of Health Research And Policy (Epidemiology) And By Courtesy, Of Statistics And Of Biomedical Data Science, Stanford University Moderator: Rafael Irizarry We are pleased to announce a new weekly Zoominar for Data Science. Rather […]
A conversation with Michael Mina, Assistant Professor Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health Moderator: Rafael Irizarry We are pleased to announce a new weekly Zoominar for Data Science. Rather than a traditional seminar format, Rafael Irizarry will moderate a Q&A with invited speakers on various topics […]
A conversation with Nicholas Reich, Associate Professor of Biostatistics, University of Massachusetts Amherst Moderator: Rafael Irizarry https://bit.ly/DSJuly21 We are pleased to announce a new weekly Zoominar for Data Science. Rather than a traditional seminar format, Rafael Irizarry will moderate a Q&A with invited speakers on various topics in data science. Join us for these interactive […]
A conversation with Caroline Buckee, Associate Professor of Epidemiology, Harvard TH Chan School of Public Health Moderator: Rafael Irizarry A recording of the talk is available on our YouTube channel.
A conversation with Emma Benn, DrPh Associate Professor, Center for Biostatistics and Department of Population Health Science and Policy Icahn School of Medicine at Mount Sinai Moderator: Rafael Irizarry A recording of the talk is available on our YouTube channel.
Wednesday August 26 from 10:00am to 12:00PM Danny Quinn will demonstrate extracting DF/HCC clinical trials data from InForm (which is the electronic data capture system (eDC)) into SAS data sets. There will also be a discussion on the attributes of the data sets and various utilities which support the extraction process.
Wednesday September 2, 2020 1:00PM ET A conversation with Alberto Cairo Knight Chair in Visual Journalism at the School of Communication of the University of Miami Moderator: Rafael Irizarry A recording of the talk is available on our YouTube channel.
Frontiers in Biostatistics Seminar Tuesday September 15, 2020 at 1:00PM Eastern Time Peter F. Thall, PhD Department of Biostatistics University of Texas M.D. Anderson Cancer Center Abstract: Conventional evaluation of a new drug, 𝐴, is done in three phases. Phase I relies on toxicity to determine a “maximum tolerable dose” (MTD) of 𝐴, in phase […]
Data Science Seminar September 22, 2020 2:00PM ET Ignaty Leshchiner, PhD Postdoctoral Fellow, Harvard Medical School/Brigham and Women's Hospital Zoom link: http://bit.ly/DSSept22 Abstract: Real-time study of tumor emergence and progression in patients will help predict and ultimately change the course of the patient's disease. This could be achieved by inferring genotypes of heterogeneous cell populations within […]
Data Science Seminar September 29, 2020 1:00PM ET Martin Aryee, PhD Assistant Professor of Pathology, Harvard Medical School Assistant Molecular Pathologist, Massachusetts General Hospital Zoom link: https://dfci.zoom.us/j/95524743149?pwd=SzN4cjJZUnhsNVl3dXNmZjZ1N3F4QT09 Abstract: The spatial organization of biological systems can impart additional functionality beyond that of the individual components. This is true at a range of scales – from cells […]
In December of 2019, we planned the next Marvin Zelen Symposium for March of 2020. At that point, the year ahead seemed to be a data spectacle waiting to happen. Think about all the events planned for 2020! Here’s what we wrote. The topic of this year's Marvin Zelen Symposium has to do with the […]
Frontiers in Biostatistics Seminar October 13, 2020 1:00PM Lu Tian, PhD Associate Professor of Biomedical Data Science in the School of Medicine Stanford University It is appealing to compared survival distributions based on restricted mean survival time (RMST), since it generates a clinically interpretable summary of the treatment effect, which can be estimated nonparametrically without […]
Data Science Seminar October 15, 2020 1:00PM ET Dominik Glodzik, PhD Repare Therapeutics Zoom link: https://bit.ly/DSOct15 Abstract: Whole genome sequences contain within them signatures of mutational processes. In particular, some of the mutation signatures relate to impaired DNA-repair in cancer cells. Accurate measurement of mutation signatures reveals the role of DNA-repair deficiencies in etiology and […]
Tuesday October 20, 2020 1:00PM ET Data Science and Academic Leadership A conversation with F. DuBois Bowman, PhD Dean of the University of Michigan School of Public Health Moderator: Rafael Irizarry Video available on our YouTube Channel.
Tuesday November 10, 2020 1:00PM ET Election Forecasting: How We Succeeded Brilliantly, Failed Miserably, or Landed Somewhere in Between A conversation with Andrew Gelman, Ph.D. Professor of Statistics and Political Science Columbia University Moderator: Rafael Irizarry RSVP at https://bit.ly/DSNov10
Tuesday November 17, 2020 1:00PM ET Communicating Statistical Findings Effectively A conversation with Professor Sir David Spiegelhalter Chair, Winton Centre for Risk and Evidence Communication Centre for Mathematical Sciences Author: The Art of Statistics Moderator: Rafael Irizarry RSVP at https://bit.ly/DSNov17
The Dana-Farber Cancer Institute Department of Data Science announces our first annual Postdoc Open House. Join us on Monday, December 7th at 1:00PM EST to explore postdoctoral opportunities in cancer research. Participating faculty include: Rafael Irizarry, PhD, Professor and Department Chair X. Shirley Liu, PhD, Professor Giovanni Parmigiani, PhD, Professor Franziska Michor, PhD, Professor Lorenzo […]
Tuesday December 8, 2020 1:00PM ET Data Science Books, Online Courses, Podcasts, and Blogs A conversation with Roger Peng, PhD Johns Hopkins Bloomberg School of Public Health Moderator: Rafael Irizarry RSVP at https://bit.ly/DSDec8
Monday, December 14, 3:00-4:30 PM ET RSVP https://bit.ly/CDSBioDec14 Speakers: Aedin Culhane, Senior Research Scientist, Dana-Farber Cancer Institute and Harvard T.H. Chan School of Public Health Isabella Grabski, PhD Student in Biostatistics, Harvard University Probabilistic gene barcodes identify cell-types in single-cell RNA-sequencing data Shannan Ho Sui, Senior Research Scientist, Harvard T.H. Chan School of Public Health […]
Tuesday December 15, 2020 1:00PM ET Data-Driven Policy in Puerto Rico A conversation with Arnaldo Cruz Director of Research and Policy of the Financial Oversight and Management Board of Puerto Rico Co-founder of ABRE Puerto Rico Moderator: Rafael Irizarry RSVP at https://bit.ly/DSDec15
Monday December 21, 2020 2:00PM ET Understanding COVID-19 Vaccine Trial Designs and Current Results A conversation with David Benkeser Assistant Professor, Biostatistics and Bioinformatics Rollins School of Public Health, Emory University Moderator: Rafael Irizarry RSVP at https://bit.ly/DSDec21
Frontiers in Biostatistics Seminar January 12, 2021 1:00PM Jing Ning, PhD Associate Professor. Department of Biostatistics Division of Quantitative Sciences The University of Texas M.D. Anderson Cancer Center Register at: https://bit.ly/FIBJan12 Abstract: Bias sampling mechanisms are commonly encountered in applications where the subjects in a target population are not given an equal chance to be selected, […]
Tuesday January 26, 2021 1:00PM ET A conversation with Daniel Larremore Assistant Professor, Department of Computer Science at University of Colorado-Boulder and BioFrontiers Institute and Kate Bubar Student, Department of Applied Mathematics, University of Colorado-Boulder Moderator: Rafael Irizarry RSVP at https://bit.ly/DSJan26 YouTube Link: https://www.youtube.com/watch?v=fJuHNNP8TLg
February 9, 2021 1:00PM ET Keaven Anderson, PhD Scientific AVP, Methodology Research, Biostatistics at Merck Group Sequential Design Assuming Delayed Benefit Abstract: We consider an asymptotic approach to design of group sequential trials with a potentially delayed effects. Logrank, weighted logrank tests and combination tests are of primary interest, but we also consider restricted mean […]
Tuesday February 23, 2021 1:00PM Eastern Time A conversation with Keolu Fox, PhD Assistant Professor, Department of Anthropology, University of California, San Diego Moderator: Aedin Culhane YouTube Link: https://www.youtube.com/watch?v=VANlStOnFPY
Frontiers in Biostatistics Seminar March 9, 2021 1:00PM Rui Duan, PhD Assistant Professor of Biostatistics Harvard TH Chan School of Public Health Distributed Statistical Learning and Inference in EHR and Other Healthcare Datasets Abstract: The growth of availability and variety of healthcare data sources has provided unique opportunities for data integration and evidence synthesis, which […]
Tuesday March 23, 2021 1:00PM Eastern Time A conversation with Timothy Rebbeck Vincent L. Gregory, Jr. Professor of Cancer Prevention, Epidemiology, Harvard T.H. Chan School Of Public Health Professor, Medical Oncology, Dana-Farber Cancer Institute Moderator: Rafael Irizarry YouTube Link: https://www.youtube.com/watch?v=Q4uBibxGf20
Frontiers in Biostatistics Seminar May 11, 2021 1:00PM Jianhua Hu, PhD Professor, Biostatistics (in Medicine and in the Herbert Irving Comprehensive Cancer Center) Director, Cancer Biostatistics Program Columbia University Register at: http://bit.ly/FIBMay21 Abstract: Applications of single-cell RNA sequencing in various biomedical research areas have been blooming. This new technology provides unprecedented opportunities to study disease […]
May 19, 2021 10:00am-12:00PM Eastern Time Fangxin Hong, PhD Senior Research Scientist Department of Data Science, Dana-Farber Cancer Institute Department of Biostatistics, Harvard T.H. Chan School of Public Health
Tuesday May 25, 2021 1:00PM ET A conversation with Cristian Tomasetti Associate Professor, Department of Oncology, Johns Hopkins Medicine, Sidney Kimmel Comprehensive Cancer Center Moderator: Giovanni Parmigiani YouTube Video now available.
June 8, 2021 1:00PM Lorenzo Trippa, PhD Associate Professor Department of Biostatistics, Harvard T.H. Chan School of Public Health Department of Data Science, Dana-Farber Cancer Institute The Use of External Control Data for Predictions and Interim Analyses in Clinical Trials YouTube video now available.
June 16, 23, and 30, 2021 10:00am-12:00PM Eastern Time Haesook Kim, PhD Principal Research Scientist Department of Data Science, Dana-Farber Cancer Institute Department of Biostatistics, Harvard T.H. Chan School of Public Health RSVP: https://bit.ly/DSTSJune16
Tuesday September 14, 2021 1:00PM Eastern Time Holly Janes, Ph.D. Professor, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center Professor, Public Health Sciences Division, Fred Hutchinson Cancer Research Center YouTube video now available.
Tuesday, October 19, 2021 1:00pm Eastern Time Meredith Regan, ScD Associate Professor Department of Data Science, Dana-Farber Cancer Institute, Harvard Medical School Treatment-free Survival as a Novel Outcome Measure of Immuno-oncology-based Therapy YouTube Link
Thursday, October 28, 2021 11:00am Eastern Time Tengfei Li Georgetown University Causal Inference Methods for Measures of Health Disparities There is increased interest in the evaluation of health disparities between different socioeconomic groups using data from observational studies. However, in the absence of randomization, the results and conclusions may be limited to associations rather than […]
The Dana-Farber Cancer Institute Department of Data Science announces its second annual Postdoc Recruitment Day to be held on Wednesday, November 3rd from 1-3pm EST. If you are interested in learning more about postdoctoral opportunities at Dana-Farber Cancer Institute and would like to learn about the research our faculty are conducting, please sign up for […]
Tuesday, November 9, 2021 1:00pm Eastern Time Suyu Liu, PhD Associate Professor Department of Biostatistics The University of Texas MD Anderson Cancer Center A Bayesian Phase I/II Trial Design for Immunotherapy Immunotherapy is an innovative treatment approach that stimulates a patient's immune system to fight cancer. It demonstrates characteristics distinct from conventional chemotherapy and stands […]
Tuesday, December 7, 2021 1:00pm Eastern Time Giovanni Parmigiani, PhD Professor Harvard T.H. Chan School of Public Health Link to YouTube Video Cancer on the Way to Mars Links: https://www.nap.edu/download/26155 https://www.env.go.jp/en/chemi/rhm/basic-info/index.html https://www.nasa.gov/feature/goddard/real-martians-how-to-protect-astronauts-from-space-radiation-on-mars https://www.nasa.gov/sites/default/files/atoms/files/space_radiation_ebook.pdf https://standards.nasa.gov/standard/nasa/nasa-std-3001-vol-1 https://spaceradiation.larc.nasa.gov/nasapapers/2020/5008710.pdf
Nathanael Fillmore is the Associate Director for Machine Learning and Advanced Analytics at the VA Boston Healthcare System’s Cooperative Studies Program Informatics Center. He leads a data science team focused on using machine learning and data science methods, in combination with the VA’s large clinical, genomic, and imaging databases, to generate knowledge and resources that […]
January 19 | 2022 | 1-4PM Eastern Time This annual symposium showcases the talent of early career investigators at the Dana-Farber/Harvard Cancer Center who work in population science, including epidemiology, biostatistics, outcomes, diversity, and cancer care delivery research, and early detection. This year, Ann Partridge, MD, MPH will be our keynote speaker. Dr. Partridge is […]
Friday February 4, 2022 1:00PM Eastern Time Register. Jian Hu PhD Candidate, Department of Biostatistics, Epidemiology and Informatics University of Pennsylvania ABSTRACT: The advent of high-throughput next-generation sequencing (NGS) technologies has transformed our understanding of cell biology and human disease. As NGS has been adopted earliest by the scientific community, its use has now become […]
Tuesday, February 8, 2022 1:00pm Eastern Time YouTube Video Elizabeth Garrett-Mayer, PhD, FSCT Vice President Center for Research and Analytics (CENTRA) Dr. Garrett-Mayer joined ASCO in 2017 as CENTRA’s Division Director for Biostatistics and Research Data Governance and became CENTRA’s first Vice President in 2022. CENTRA leads ASCO’s research efforts, including the TAPUR Study, ASCO’s […]
Tuesday February 15, 2022 1:00PM Eastern Time William Lotter, PhD Vice President of Machine Learning, RadNet, Inc. Chief Technology Officer & Co-Founder, DeepHealth, Inc. Register. Screening mammography has been estimated to reduce breast cancer mortality by 20-40%, but significant opportunities remain for improving access and overall quality. Artificial intelligence (AI) has the potential to deliver […]
Thursday February 24, 2022 1:00PM Eastern Time Michele Peruzzi, PhD Postdoctoral Associate, Department of Statistical Science, Duke University Register. Abstract: In this talk, I will consider the problem of fitting Bayesian models with spatial random effects to large scale multivariate multi-type data from satellite imaging, land-based weather and air quality sensors, and citizen science, with […]
Monday February 28, 2022 1:00PM Eastern Time Genevieve Stein-O'Brien Instructor, Johns Hopkins University, School of Medicine Department of Oncology, Division of Biostatistics and Bioinformatics; Department of Neuroscience; and McKusick-Nathans Department of Genomic Medicine Assistant Director, Johns Hopkins University Single Cell Consortium Register. Abstract: As the single-cell field races to characterize each cell type, state, and […]
Tuesday, March 1, 2022 1:00pm Eastern Time Rebecca A. Hubbard, PhD Professor of Biostatistics University of Pennsylvania Perlman School of Medicine YouTube Video Abstract: Opportunities to use real-world data (RWD), including electronic health records (EHR) and medical claims data, have exploded over the past decade. The Covid-19 pandemic has provided a particularly dramatic illustration of […]
Friday, March 4, 2022 12:00PM Eastern Time Ani Eloyan, PhD Assistant Professor Department of Biostatistics, Brown University Register. Abstract: Cancer patients routinely undergo radiological evaluations where images of various modalities including computed tomography, positron emission tomography, and magnetic resonance images are collected for diagnosis and for evaluation of disease progression. Tumor characteristics, often referred to […]
Monday March 7th, 2022 1:00PM Eastern Time Ava Soleimany, PhD Senior Researcher, Biomedical Machine Learning Group at Microsoft Research, New England Abstract: Precision cancer medicine envisions a world where diagnostic and therapeutic opportunities are intelligently tailored to individual patient needs. Achieving this vision necessitates access to high quality, accurate, and individualized information about disease state. […]
The growing availability of informative datasets and software tools has led to increased reliance on data visualizations across many industries, academia, and government. News organizations are increasingly embracing data journalism and including effective infographics as part of their reporting, while in research we increasingly rely on data visualization to assess data quality and describe and […]
Maya Ramchandran Data Scientist, ZephyrAI Abstract: Adapting machine learning algorithms to better handle clustering or other partition structure within training data sets is important across a wide variety of biological applications. We first consider the task of learning prediction models when multiple training studies are available. We present a novel weighting approach for constructing tree-based ensemble […]
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