Genomics Expert Jeremy Simon, PhD Joins Data Science

The Department of Data Science welcomed Jeremy M. Simon, PhD on May 1, 2023.

Dr. Simon’s research focuses on the genetic and environmental effects on gene expression and gene regulation in human disease. He is currently Associate Professor, Genetics at University of North Carolina (UNC) Chapel Hill, where he directs the UNC Neuroscience Center Bioinformatics Core and serves as co-Principal of the UNC School of Medicine Bioinformatics and Analytics Research Collaborative (BARC).

“We are delighted that Dr. Simon is joining the Department of Data Science,” said Department Chair Rafa A. Irizarry, PhD. “He is an expert in genomics and a superb collaborator.”

Team science is central to Dr. Simon’s research approach. He has collaborated with dozens of investigators and laboratories on the design, execution, analysis, and biological interpretation of high-throughput sequencing-based studies. Using integrative high-throughput sequencing-based approaches (ATAC-seq, ChIP-seq, RNA-seq, and others in bulk and single cells), Dr. Simon has studied chromatin and gene expression dysregulation in numerous disease contexts including Renal Cell Carcinoma, Ewing Sarcoma, breast cancer, autism, and Crohn’s disease. Through this work, he and his collaborators have uncovered novel disease mechanisms, as well as molecular and genetic disease subtypes.

“I am very excited to join Dana-Farber,” said Dr. Simon, who trained under Dana-Farber alumnus Dr. Ian Davis at UNC-Chapel Hill. “I learned so much during my time at UNC. It taught me the ins and outs of genomics, how these data can help us solve big questions in cancer, and how important team science is to basic and translational research. I look forward to diving in and collaborating broadly across the Institute.”

Dr. Simon will be an independent investigator in Data Science with a Senior Research Scientist appointment at the Harvard T.H. Chan School of Public Health. He received a PhD in Bioinformatics and Computational Biology from UNC-Chapel Hill.

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