Frontiers in Biostatistics Seminar

March 9, 2021
1:00PM

Rui Duan, PhD
Assistant Professor of Biostatistics
Harvard TH Chan School of Public Health

Distributed Statistical Learning and Inference in EHR and Other Healthcare Datasets

Abstract: The growth of availability and variety of healthcare data sources has provided unique opportunities for data integration and evidence synthesis, which can potentially accelerate knowledge discovery and enable better clinical decision making.  However, many practical and technical challenges, such as data privacy, high-dimensionality and heterogeneity across different datasets, remain to be addressed. In this talk, I will introduce several methods for effective and efficient integration of electronic health records and other healthcare datasets. Specifically, we develop communication-efficient distributed algorithms for jointly analyzing multiple datasets without the need of sharing patient-level data. Our algorithms are able to account for heterogeneity across different datasets. We provide theoretical guarantees for the performance of our algorithms, and examples of implementing the algorithms to real-world clinical research networks.

YouTube Link: https://www.youtube.com/watch?v=IscQ3ruxl1o