Frontiers in Biostatistics: Tree-based Ensembling Strategies for Handling Heterogeneous Data

Maya Ramchandran Data Scientist, ZephyrAI Abstract: Adapting machine learning algorithms to better handle clustering or other partition structure within training data sets is important across a wide variety of biological applications. We first consider the task of learning prediction models when multiple training studies are available. We present a novel weighting approach  for constructing tree-based ensemble […]

It’s All Relative: Testing Differential Abundance in Compositional Microbiome Data

Frontiers in Biostatistics Seminar Series Tuesday September 13, 2022 1:00PM Eastern Time Yijuan Hu, Ph.D. Associate Professor Department of Biostatistics and Bioinformatics Rollins School of Public Health Emory University Register for Zoom link Abstract: Studies on the human microbiome have revealed that differences in microbial communities are associated with many human disorders such as inflammatory […]

Design and Implementation of Bayesian Adaptive Phase I Trials in Oncology using the DEDUCE Application

Center of Life Sciences, Room 11081 3 Blackfan Circle, Boston, MA, United States

Frontiers in Biostatistics Seminar Series Tuesday November 1, 2022 1:00PM Eastern Time Register for in-person or virtual attendance. Wendy London, PhD Associate Professor, Harvard Medical School Director of Biostatistics, Boston Children’s Hospital Clement Ma, PhD Assistant Professor, University of Toronto Independent Scientist, CAMH

A Nonparametric Bayesian Approach to Use RWD in Clinical Trial Design

Frontiers in Biostatistics Seminar Tuesday January 24, 2023 1:00PM Eastern Time Click to watch the YouTube video. Peter Mueller, PhD Professor Department of Statistics and Data Sciences Department of Mathematics University of Texas at Austin  

Using the Case Study of Atezolizumab Development to Rethink Early Phase Oncology Trial Design

Frontiers in Biostatistics Seminar Tuesday February 14, 2023 1:00PM Eastern Time YouTube video Emily Zabor, DrPH Assistant Staff Biostatistician Department of Quantitative Health Sciences at the Cleveland Clinic, with a joint appointment in the Taussig Cancer Institute Assistant Professor of Medicine, the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University

Computation of High-Dimensional Penalized Generalized Linear Mixed Models

Thursday March 2, 2023 1:00pm ET Hillary Heiling Biostatistics PhD candidate University of North Carolina Chapel Hill. Add to calendar Hillary’s statistical focus has primarily been in cancer-related research, both through her graduate research assistant role in the Lineberger Comprehensive Cancer Center as well as her personal research applications. In cancer research as well as […]

Dimension Reduction of Longitudinal Microbiome Data

Frontiers in Biostatistics Seminar Wednesday March 29, 2023 1:00PM Eastern Time Pixu Shi, PhD Assistant Professor of Biostatistics & Bioinformatics Division of Integrative Genomics Department of Biostatistics & Bioinformatics Duke University School of Medicine Abstract: The analysis of longitudinal microbiome is crucial to the understanding of how microbiome changes over time. It often requires careful […]

Model-robust and Efficient Covariate Adjustment for Cluster-randomized Experiments

Frontiers in Biostatistics Seminar Tuesday May 9, 2023 1:00PM Eastern Time Join the Zoom. Fan Li, PhD Assistant Professor of Biostatistics, Yale School of Public Health Cluster-randomized experiments are increasingly used to evaluate interventions in routine practice conditions, and researchers often adopt model-based methods with covariate adjustment in the statistical analyses. However, the validity of model-based […]

Forecasting pancreatic carcinogenesis from spatial multi-omics

Center of Life Sciences, Room 11081 3 Blackfan Circle, Boston, MA, United States

Frontiers in Biostatistics Seminar Tuesday September 26, 2023 @ 10am ET Center for Life Sciences Building, Room 11081 Elana Fertig, PhD Division Director of Oncology Quantitative Sciences, Professor of Oncology Johns Hopkins University YouTube Video Combining genomics with mathematical modeling provides a forecast system that can yield computational predictions to anticipate cancer progression and therapeutic […]

AI in Medical Imaging: Current State & Future Opportunities

Center of Life Sciences, Room 11081 3 Blackfan Circle, Boston, MA, United States

Frontiers in Biostatistics Seminar Tuesday October 24, 2023 @ 1pm ET Center for Life Sciences Building, Room 11081 William Lotter, PhD Assistant Professor, Dana-Farber Cancer Institute and Harvard Medical School YouTube Video Want to get our weekly events newsletter? Click here!

Single-cell Multiomic Exploration of Oncogenic and Immunologic Programs in Melanoma and CLL

Center for Life Sciences, Zelen Commons 3 Blackfan Circle, Boston, MA

Elevate @ Eleven: Comp Bio Connections Wednesday November 8th, 2023 12:00-1:00PM In-person only, Zelen Commons, 11th floor of the Center for Life Sciences Building Jeremy Simon Senior Research Scientist, Harvard T.H. Chan School of Public Health Lunch is provided.