Flexible and coherent test/estimation procedure
Horiguchi M, Cronin A, Takeuchi M, Uno H. A flexible and coherent test/estimation procedure based on restricted mean survival times for censored time-to-event data in randomized clinical trials. Statistics in Medicine 2018. doi:10.1002/sim.7661.
- R contributed package survRM2adapt Flexible and Coherent Test/Estimation Procedure Based on RMST (Miki Horiguchi, Hajime Uno)
Validating prediction model
Uno H, Inoue E. On estimating predictive performance measure of risk prediction models with external validation data. JSM proceedings 2017.
- R contributed package APPEstimation Adjusted Prediction model Performance Estimation (Eisuke Inoue, Hajime Uno)
- Vignette for APPEstimation (Eisuke Inoue, Hajime Uno)
Restricted Mean Survival Time
Uno H, Wittes J, Fu H, Solomon SD, Claggett B, Tian L, Cai T, Pfeffer MA, Evans SR, Wei LJ. Alternatives to Hazard Ratios for Comparing the Efficacy or Safety of Therapies in Noninferiority Studies. Annals of Internal Medicine 2015. 163(2), 127–12.
- R contributed package survRM2 Comparing RMST (Hajime Uno, Lu Tian, Angel Cronin, Chakib Battioui, Miki Horiguchi)
- Vignette for survRM2 (Hajime Uno)
- STRMST2 (Stata version of survRM2)
- SAS version of survRM2 made by Chakib Battioui
- R contributed package SSRMST Sample size calculation using RMST (Miki Horiguchi, Hajime Uno)
- Vignette for SSRMST (Miki Horiguchi, Hajime Uno)
Uno H, Claggett B, Tian L, Inoue E, Gallo P, Miyata T, Schrag D, Takeuchi M, Uyama Y, Zhao L, Skali H, Solomon S, Jacobus S, Hughes M, Packer M, Wei LJ. Moving beyond the hazard ratio in quantifying the between-group difference in survival analysis. Journal of Clinical Oncology 2014, 32(22):2380-2385.
- R contributed package surv2sampleComp Inference for model-free between-group parameters for censored survival data (Lu Tian, Hajime Uno, Miki Horiguchi)
Versatile test
Uno H, Tian L, Claggett B, We LJ. A versatile test for equality of two survival functions based on weighted differences of Kaplan-Meier curves, Statistics in Medicine, 2015; 34(28):3680-95
- R contributed package survAWKMT2 Two-sample tests base on Differences of Kaplan Meier Curves
(Miki Horiguchi, Hajime Uno)
IDI/NRI with censored survival data
Uno H, Tian L, Cai T, Kohane IS, Wei LJ. A unified inference procedure for a class of measures to assess improvement in risk prediction systems with survival data. Statistics in Medicine. 2013; 32(14):2430-2442. doi: 10.1002/sim.5647.
R contributed package survIDINRI (example) IDI and NRI for comparing competing risk prediction models with censored survival data (Hajime Uno, Tianxi Cai)
C-index for censored survival data
Uno H, Cai T, Pencina MJ, D'Agostino RB, and Wei LJ. On the C-Statistics for Evaluating Overall Adequacy of Risk Prediction Procedures with Censored Survival Data. Statistics in Medicine. 2011;30:1105-117.
R contributed package survC1 (example) C-statistics for risk prediction models with censored survival data (Hajime Uno)
SAS version of survC1 contributed by Brian Starr
Time-dependent covariates
SAS program (by Yuuki Yoshida and Takenobu Tasaki)
References:
- Mantel and Byar. Evaluation of response-time data involving transient status: an illustration using heart-transplant data Kaplan Meier Curve. JASA 1974.
- Simon and Makuch A non-parametric graphical representation of the relationship responder bias. Statistics in medicine 1984
Integrated Difference of Two Survival Functions
Zhao L, Tian L, Uno H, Solomon S, Pfeffer M, Schindler J, Wei LJ. Utilizing the Integreted Difference of Two Survival Functions to Quantify the Treatment Contrast for Designing, Monitoring and Analyzing a Comparative Clinical Study. Clinical Trials. 2012;9(5):570-7
R code by Dr. Lihui Zhao
- R function: FUN-IRD.R
- Example: Sample-IRD.R
Subject-Specific Incremental Values of New Maker
Uno H, Cai T, Tian L, and Wei LJ. Graphical Procedures for Evaluating Overall and Subject-Specific Incremental Values from New Predictors with Censored Event Time Data. Biometrics. 2011;67:1389-96.