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DTSTART;TZID=America/New_York:20260409T160000
DTEND;TZID=America/New_York:20260409T170000
DTSTAMP:20260503T091142
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SUMMARY:Factor Analysis and Questions of Causation
DESCRIPTION:HSPH Biostatistics and DFCI Data Science Colloquium\nThursday April 9 at 4:00pm\nHSPH\, FXB 301 \nTyler VanderWeele\, PhD\, John L. Loeb And Frances Lehman Loeb\, Professor of Epidemiology\, Faculty Affiliate – Department of Biostatistics\, Harvard T.H. Chan School of Public Health \nFactor analysis is often employed to evaluate the extent to which a single factor suffices to explain the variation in individual indicators. \nHowever\, often the resulting factors are interpreted as corresponding to a structural univariate latent variable that is itself causally efficacious. This assumption is so strong that it has empirically testable implications\, even though the supposed latent variable is unobserved; statistical tests are proposed that can often reject this assumption. Factor analysis also suffers from the inability to distinguish between associations arising from causal versus conceptual relations; if two supposed factors were to causally affect one another then\, over time\, the process will converge to a factor model wherein only a single factor can be detected. When both positively and negatively worded items are used\, factor analysis can also suggest that two factors are present even if the data were in fact generated by one. Examples of these various phenomena are given. \nDespite these limitations\, factor analyses can nevertheless often be informative\, but requires an appropriate reinterpretation of results as reflecting a combination of causal\, conceptual\, and distributional relations. \n\nColloquium Seminar Series \n\n 
URL:https://ds.dfci.harvard.edu/event/factor-analysis-and-questions-of-causation/
CATEGORIES:Seminar
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DTSTART;TZID=America/New_York:20260416T160000
DTEND;TZID=America/New_York:20260416T170000
DTSTAMP:20260503T091142
CREATED:20260403T131453Z
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SUMMARY:When Large p Is a Blessing
DESCRIPTION:HSPH Biostatistics and DFCI Data Science Colloquium\nThursday April 9 at 4:00pm\nHSPH\, FXB 301 \nZhijin Wu\, PhD\, Professor of Biostatistics\, Brown University \nBiomedical research has benefited tremendously from the breakthroughs in biotechnology in the last two decades that enabled simultaneous quantifications of a large number of biomolecules (DNA/RNA/proteins). Such data collected at the -omics scale often have a “small N large p” structure and the “large p” is often seen as a curse of Dimensionality. \nHowever\, sometimes the nature of high throughput data acquisition can be useful and provides information that is only accessible in “large p” settings. I will present several examples of our methodology development that takes advantage of the “large p” nature in genomic studies that lead to improved detection of molecular signals. \n\nColloquium Seminar Series \n\n 
URL:https://ds.dfci.harvard.edu/event/when-large-p-is-a-blessing/
CATEGORIES:Seminar
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DTSTART;TZID=America/New_York:20260423T160000
DTEND;TZID=America/New_York:20260423T170000
DTSTAMP:20260503T091142
CREATED:20260417T145833Z
LAST-MODIFIED:20260424T133622Z
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SUMMARY:Evidence Triangulation in Dementia Research
DESCRIPTION:HSPH Biostatistics and DFCI Data Science Colloquium\nThursday April 23 at 4:00pm\nHSPH\, FXB 301 \nMaria Glymour\, ScD\, Chair and Professor of Epidemiology\, Boston University School of Public Health \nResearch on cognitive aging\, including development of neurodegenerative diseases such as Alzheimer’s\, is fraught with causal inference challenges. This talk will briefly review why identifying the causes and potential prevention strategies for dementia is particularly challenging. I will discuss a framework for evidence triangulation and offer examples of promising approaches in dementia research.
URL:https://ds.dfci.harvard.edu/event/evidence-triangulation-in-dementia-research/
CATEGORIES:Seminar
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DTSTART;TZID=America/New_York:20260430T160000
DTEND;TZID=America/New_York:20260430T170000
DTSTAMP:20260503T091142
CREATED:20260417T150212Z
LAST-MODIFIED:20260424T133609Z
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SUMMARY:Building Data Analysis Proofs
DESCRIPTION:HSPH Biostatistics and DFCI Data Science Colloquium\nThursday April 30 at 4:00pm\nHSPH\, FXB 301 \nRoger Peng\, PhD\, Professor of Statistics and Data Sciences\, University of Texas at Austin \nData analyses are often constructed in an imperative manner\, where commands representing actions taken on the data are issued sequentially. The publication of these commands\, along with the data\, is essential to the reproducibility of the analysis by others. However\, simply presenting the code and the results of running the code can hide important details about the data analyst’s premises\, expectations\, and assumptions about the data. Understanding this analysis reasoning can be critical to evaluating the quality of an analysis and for suggesting possible improvements. We argue that a formal representation of a data analysis that externalizes its logical construction offers more useful information for statically illustrating an analyst’s reasoning. Such a formal representation would allow for the evaluation of some aspects of a data analysis without the need for the data\, the visualization of the logical connections leading to a conclusion\, and the ability to assess the sensitivity of an analyst’s assumptions to unexpected features in the data. In this talk I will describe an implementation of this formal representation and how it might be applied to some common data analysis tasks. \n\nColloquium Seminar Series
URL:https://ds.dfci.harvard.edu/event/building-data-analysis-proofs/
CATEGORIES:Seminar
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DTSTART;TZID=America/New_York:20260616T130000
DTEND;TZID=America/New_York:20260616T170000
DTSTAMP:20260503T091142
CREATED:20260501T151415Z
LAST-MODIFIED:20260501T151458Z
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SUMMARY:2026 Marvin Zelen Symposium
DESCRIPTION:We invite you to attend the Marvin Zelen Memorial Symposium\, an event that celebrates the life and contributions of a remarkable figure in the field of statistics. This symposium will be held on Tuesday\, June 16th\, 2026\, from 1:00 PM to 5:00 PM ET at the Helen G. Drinan Hall at Simmons University. \nThe Marvin Zelen Memorial Symposium is an opportunity for statisticians\, researchers\, and professionals in the field to come together and engage in thought-provoking discussions and presentations. We have curated an exceptional lineup of speakers who will share their expertise and insights. \nTo ensure your attendance\, please RSVP by clicking on the following link: https://bit.ly/zelen26. \nA reception will follow the symposium. \n2026 Speakers \nMaria Jones\, MA\nSenior Economist in the Development Impact (DIME) department at the World Bank \nChirag Patel\, PhD\nAssociate Professor of Biomedical Informatics\, Harvard Medical School \nVictoria Stodden\, PhD\nAssociate Professor\, Daniel J. Epstein Department of Industrial & Systems Engineering\, at the University of Southern California \nOlga Vitek\, PhD\nRaymond Bradford Bradstreet Professor\, Director\, Barnett Institute for Chemical and Biological Analysis\, Khoury College of Computer Sciences\, Northeastern University \n 
URL:https://ds.dfci.harvard.edu/event/2026-marvin-zelen-symposium/
LOCATION:Simmons University\, 300 The Fenway\, Boston\, MA\, United States
CATEGORIES:Symposium
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